I once happened to share a social circle with a stone-cold narcissist, and he seemed mildly annoyed whenever I existed in the same room as him. I try to be friends with literally every person I meet, but this narcissist dude acted genuinely disgusted by me.
I've also got a pattern of annoying the shit out of low-openness nurses. Conscientious and extroverted people, to be sure, but they're not used to dealing with a person like me who runs on high-octane speculative thinking.