I'm thinking meaning is similar to this: You have some best guesses right now about what is meaningful, and that's all that's required for you to move in a direction. And on the way you may learn things or you may change yourself, and then your direction changes.
But that's ok, because the point isn't the arriving, it's the going. I think it's about living a life which feels meaningful, and WANTING to do unpleasant things because they feel meaningful to you. So your values don't need to be constant.