You can still compromise with them by giving them incremental progress towards their goal in exchange for things you want.
Say, a limitation on late-term abortion in exchange for increased unemployment funding.
But be careful lest you piss of your own base.
But just assuming that every Trump voter is a White Supremacist is no good.
If 46% of the country were _actuality_ White Supremacists, they would have a commanding plurality in Congress. Everyone would have to suck up to them. They would be way better at pushing their agenda.