RT @AlexTISYoung
A subtle point that this paper makes concrete is that confounding in the GWAS used to make a PGS complicates the interpretation of within-family estimates of PGS associations across traits: i.e., just because PGS of trait 1 predicts trait 2 within-family, that doesn't imply… https://twitter.com/i/web/status/1630380670311874561